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Myofol is a food supplement that optimizes ovarian function and regulates menstrual cycles, allows normal ovulation and corpus luteum function with elevated Prolactin, protects and helps to improve the eggs quality and alleviates PCOS (Polycystic Ovary Syndrome) symptoms. It also promotes healthy follicles in the ovaries, ensures healthy fertility, conception, and pregnancy. It contains ingredients that are useful for fertility, such as Myo-Inositol, White Kidney Beans and Folic Acid.
White Kidney Beans
- The main claim of using White Kidney Beans is to induce weight loss and reduce the postprandial spike in blood glucose levels.
- According to Food Science & Nutrition that the regular intake of white kidney beans extract induces weight loss.
This study contained a randomized, double-blinded, placebo-controlled study was conducted on obese volunteers to evaluate the degree of significate weight loss by regular intake White Kidney Bean cultivated from Southwestern region of China.
The volunteers were divided into two groups, homogeneous for age, gender and body weight. White Kidney Bean or placebo was given 2,400 mg per day before each daily meal for 35 consecutive days.
Each subject’s body weight, fat mass, body mass index, blood biochemical parameters, skinfold fat thickness, and waist/hip circumferences were monitored and analyzed.
The study suggests that White Kidney Beans may be a promising dietary supplement for weight loss in obese individuals. Its mechanism of action is likely related to its ability to inhibit alpha-amylase, an enzyme involved in the breakdown of carbohydrates. Further research is needed to confirm these findings and explore the long-term effects of PVE on weight management.
Relevance to PCOS:
Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder that often includes symptoms such as insulin resistance, weight gain and difficulty with weight management. Given that insulin resistance is a key factor in PCOS, managing blood glucose levels is crucial. The ability of white kidney bean extract to reduce postprandial glucose spikes and aid in weight loss may offer significant benefits for women with PCOS. By potentially improving insulin sensitivity and reducing weight, white kidney beans could help address two major concerns in PCOS management.
Myo-Inositol
Myo-inositol plays a crucial role in fertility and supports a healthy pregnancy by acting as a second messenger for gonadotropins and insulin. It ensures the proper development of oocytes and the progression of embryogenesis. Research shows that myo-inositol supplementation enhances the likelihood of achieving pregnancy and lowers the risk of negative maternal and neonatal outcomes. Specifically, it helps induce ovulation and restore the normal menstrual cycle in infertile women, especially those with PCOS. Additionally, myo-inositol supplementation benefits women undergoing assisted reproductive technologies (ART) by improving oocyte and embryo quality. During pregnancy, it can reduce the risk of metabolic conditions such as gestational diabetes mellitus (GDM), which are associated with miscarriages and stillbirths. Moreover, myo-inositol may decrease the risk of neural tube defects (NTDs) in women who are resistant to folate.
Folic Acid
For over 30 years, the US Public Health Service has advised individuals capable of becoming pregnant to consume folic acid to prevent neural tube defects (NTDs). Since the neural tube forms within 28 days after conception, early folic acid intake is crucial. Fortification with FA is particularly beneficial in populations with limited access to folic acid-rich foods or supplements.
This review examines the current state of mandatory folic acid fortification in 71 countries and evaluates the impact of these programs. Findings include:
- Reduction in NTD Rates: Fortification has led to up to a 78% decrease in NTDs.
- Increased Blood Folate Levels: Red blood cell folate concentrations increased approximately 1.47-fold following fortification.
SUMMARY POINTS
- Mandatory folic acid fortification has significantly reduced the prevalence of neural tube defects (NTDs), increased blood folate levels by less than twofold, and has not been associated with any known increased risk of adverse outcomes when used at recommended dosages.
- High-quality research examining the interactions between folic acid and vitamin B12, with careful measurement and control of intake, metabolism and excretion, could enhance the benefits of fortification and address concerns about its safety.
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