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Dextromethorphan (DXM), is a non-opioid derivative of morphine. It acts on the central nervous system by suppressing the cough reflex through its action on the medulla, a part of the brain that controls coughing. It is a common ingredient in over-the-counter cough syrups.
DXM is primarily used to relieve coughs caused by colds, the flu, or other respiratory conditions.
It is often combined with other medications such as antihistamines, decongestants, and pain relievers in multi-symptom cold and flu products.
DXM has several disadvantages and potential risks. It has a high potential for abuse due to its euphoric and hallucinogenic effects at high doses, which can lead to psychological dependency. Adverse effects include dizziness, nausea, vomiting, drowsiness, and in severe cases, confusion, agitation, impaired motor function, and respiratory depression.
DXM can interact dangerously with other drugs, particularly monoamine oxidase inhibitors (MAOIs) and certain antidepressants, increasing the risk of serotonin syndrome and other adverse effects. Its use in children, pregnant, and breastfeeding women is controversial due to potential serious side effects and lack of proven efficacy. By suppressing coughs, it can mask symptoms of more serious underlying conditions, potentially delaying diagnosis and treatment.
Additionally, DXM can cause mood changes, irritability, agitation, and in extreme cases, psychosis. Legal and regulatory measures, such as age restrictions and prescription-only status in some regions, are often necessary to control misuse and mitigate risks associated with its use.
Natural cough syrups that do not contain dextromethorphan, like CEDAL cough syrup developed by CEDEM AG Switzerland, offer several advantages, including fewer side effects, a lower risk of abuse, and suitability for a broader range of people, including children starting from 1 year old and adults. Its harmonious combination of honey and chamomile, complemented by the essence of lemon and strawberry, provides additional health benefits such as antimicrobial and anti-inflammatory effects. Additionally, CEDAL is a 100% natural product that is alcohol-free, non-drowsy, supports the immune system with a source of vitamin C, and is very tasty with its strawberry flavor. It is also non-GMO, gluten-free, and free of preservatives, artificial colors, and artificial flavors.
References:
https://www.drugs.com/dextromethorphan.html
https://www.webmd.com/drugs/2/drug-363/dextromethorphan-hbr-oral/details
